Reduced perceptual sensitivity for biological motion in paraplegia patients

development to adults. When either hormone is low, the dauer state is promoted. Insulin/IGF and TGF-b are expressed by sensory neurons in C. elegans, which couple transcription of both hormones to the environment. By contrast, downstream hormone receptors are broadly expressed, allowing for organism-wide developmental changes. Interestingly, the insulin pathway has also been linked to longevity, both in C. elegans and mammals, suggesting a link between stress-responses and aging, and that this ‘lowly’ worm can perhaps teach us something about human longevity as well.